High genetic diversity including potential new subtypes of Hepatitis C virus genotype 6 in Lao People’s Democratic Republic.

  • Clinical and Applied Virology
December 01, 2011 By:
  • Hubschen JM
  • Jutavijittum P
  • Thammavong T
  • Samountry B
  • Yousukh A
  • Toriyama K
  • Sausy A
  • Muller CP.

Sera from 105 anti-HCV-positive first-time blood donors collected in 2004, 2005 and 2008 in different provinces in Laos were investigated by PCR. Forty-five samples were positive for HCV (42.86%); two belonged to subtype 1b (2/45, 4.4%) and all others to genotype 6 (43/45, 95.6%), including subtypes 6b, 6h, 6k, 6l, 6n and 6q. Three groups of sequences were not clearly attributable to any genotype 6 subtype, two of which may be regarded as candidates for new subtypes of genotype 6. Two samples were mixed infected with different subtypes or clusters of genotype 6 viruses.

2011 Dec. Clin Microbiol Infect.17(12):E30-E34. Epub 2011 Sep 29.
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