Petr Nazarov
Latest publications
AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion.
- NORLUX Neuro-Oncology Laboratory
- Multiomics Data Science
- Quantitative Biology Unit
- Proteomics of Cellular Signaling
2020 Dec. Nat Commun.11(1):6366.
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
- NORLUX Neuro-Oncology Laboratory
- Translational Radiomics
- Neuro-Immunology Group
- Computational Biomedicine
- Multiomics Data Science
- Luxembourg Center of Neuropathology
- Personalized Therapy Discovery
2020 Dec. Acta Neuropathol.140(6):919-949. Epub 2020 Oct 3.
Systematic transcriptional profiling of responses to STAT1- and STAT3-activating cytokines in different cancer types.
- Multiomics Data Science
- Quantitative Biology Unit
2020 Nov. J Mol Biol.432(22):5902-5919. Epub 2020 Sep 18.
Reference-free deconvolution, visualization and interpretation of complex DNA methylation data using DecompPipeline, MeDeCom and FactorViz.
- Multiomics Data Science
- Computational Biomedicine
2020 Oct. Nat Protoc.15(10):3240-3263. Epub 2020 Sep 25.
Community assessment of the predictability of cancer protein and phosphoprotein levels from genomics and transcriptomics.
- Multiomics Data Science
- Quantitative Biology Unit
2020 Aug. Cell Syst.11(2):186-195 e9. Epub 2020 Jul 24.
Hypoxia-induced autophagy drives colorectal cancer initiation and progression by activating the PRKC/PKC-EZR (ezrin) pathway.
- Tumor Immunotherapy and Microenvironment
- Multiomics Data Science
- Integrated BioBank of Luxembourg
- Luxembourg Center of Neuropathology
2020 Aug. Autophagy.16(8):1436-1452. Epub 2019 Nov 27.
Hub genes in a pan-cancer co-expression network show potential for predicting drug responses.
- Computational Biomedicine
- NORLUX Neuro-Oncology Laboratory
- Proteomics of Cellular Signaling
2020 Jul. F1000Res.7:1906.
Independent component analysis of cancer transcriptomes: optimization of parameters and improvement of interpretability. In Computer Technologies and Data Analysis (CTDA'2020) : Materials of II International Scientific-Practical Conference, Minsk, 23-24 April, 2020. (Book Chapter)
- Multiomics Data Science
2020 Jul. Bishkek VA and Skakun V, eds. Minsk: BSU, 2020. p.170-173. ISBN 978-985-566-942-6.
Deconvolution of “big data” in cancer genomics: from pancancer level to single cells. In Computer Technologies and Data Analysis (CTDA'2020) : Materials of II International Scientific-Practical Conference, Minsk, 23-24 April, 2020. (Book Chapter)
- Multiomics Data Science
- Computational Biomedicine
- Quantitative Biology Unit
2020 Jul. Bishkek VA and Skakun V, eds. Minsk: BSU, 2020. p.7-11. ISBN 978-985-566-942-6.
Guidelines for cell-type heterogeneity quantification based on a comparative analysis of reference-free DNA methylation deconvolution software.
- Computational Biomedicine
- Multiomics Data Science
2020 Jan. BMC Bioinformatics.21(1):16.
Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients.
- Multiomics Data Science
- Computational Biomedicine
- Proteomics of Cellular Signaling
2019 Sep. BMC Med Genomics.12(1):132.
Independent component analysis for unraveling the complexity of cancer omics datasets.
- Multiomics Data Science
2019 Sep. Int J Mol Sci.20(18).
The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein-protein interaction in glioblastoma.
- NORLUX Neuro-Oncology Laboratory
- Multiomics Data Science
- Immuno-Pharmacology and Interactomics
2019 Sep. Neurooncol Adv.1(1):vdz024.
Power-law behavior of the alternative splicing of exons in human transcriptome.
- Multiomics Data Science
2019 Sep. Annu Res Rev Biol.32(6):1-13.
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment.
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
- Competence Center for Methodology and Statistics
- Platform National Cytometry
2019 Apr. Nat Commun.10(1):1787.
A DNA repair and cell-cycle gene expression signature in primary and recurrent glioblastoma: prognostic value and clinical implications.
- DNA Repair and Chemoresistance
- Computational Biomedicine
- NORLUX Neuro-Oncology Laboratory
2019 Mar. Cancer Res.79(6):1226-1238. Epub 2019 Jan 23.
Tumor suppressor miR-215 counteracts hypoxia-induced colon cancer stem cell activity.
- Multiomics Data Science
2019 Feb. Cancer Lett.450:32-41. Epub 2019 Feb 18.
RNAi/CRISPR Screens: from a Pool to a Valid Hit.
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
- DNA Repair and Chemoresistance
2019 Jan. Trends Biotechnol.37(1):38-55. Epub 2018 Aug 31.
The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by alpha-PD-L1 or alpha-IL6 antibodies.
- Multiomics Data Science
2018 Nov. J Leukoc Biol.104(5):969-985. Epub 2018 Jul 24.
Cytokine-mediated modulation of the hepatic miRNome: miR-146b-5p is an IL-6-inducible miRNA with multiple targets.
- Computational Biomedicine
2018 Nov. J Leukoc Biol.104(5):987-1002. Epub 2018 Aug 26.