Francisco Azuaje

Latest publications

Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment.

  • Neuro-Oncology Laboratory
  • Computational Biomedecine
  • Competence Center for Methodology and Statistics
  • Dimensional Immuno-Cytometry
April 16, 2019
2019 Apr. Nat Commun.10(1):1787.
By:
  • Dirkse A
  • Golebiewska A
  • Buder T
  • Nazarov PV
  • Muller A
  • Poovathingal S
  • Brons NHC
  • Leite S
  • Sauvageot N
  • Sarkisjan D
  • Seyfrid M
  • Fritah S
  • Stieber D
  • Michelucci A
  • Hertel F
  • Herold-Mende C
  • Azuaje F
  • Skupin A
  • Bjerkvig R
  • Deutsch A
  • Voss-Bohme A
  • Niclou SP.

Analysis of correlation-based biomolecular networks from different omics data by fitting stochastic block models [version 1; peer review: awaiting peer review].

  • Computational Biomedecine
April 14, 2019
2019 Apr. F1000Res.8(465).
By:
  • Baum K
  • Rajapakse J
  • Azuaje F.

Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis.

  • Neuro-Oncology Laboratory
  • Computational Biomedecine
April 10, 2019
2019 Apr. Acta Neuropathol Commun.7(1):55.
By:
  • Sundstrom T
  • Prestegarden L
  • Azuaje F
  • Aasen SN
  • Rosland GV
  • Varughese JK
  • Bahador M
  • Bernatz S
  • Braun Y
  • Harter PN
  • Skaftnesmo KO
  • Ingham ES
  • Mahakian LM
  • Tam S
  • Tepper CG
  • Petersen K
  • Ferrara KW
  • Tronstad KJ
  • Lund-Johansen M
  • Beschorner R
  • Bjerkvig R
  • Thorsen F.

Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma.

  • Computational Biomedecine
  • Neuro-Oncology Laboratory
April 08, 2019
2019 Apr. Neuro Oncol. [Epub ahead of print].
By:
  • Hossain JA
  • Latif MA
  • Ystaas LAR
  • Ninzima S
  • Riecken K
  • Muller A
  • Azuaje F
  • Joseph JV
  • Talasila KM
  • Ghimire J
  • Fehse B
  • Bjerkvig R
  • Miletic H.

Hub genes in a pan-cancer co-expression network show potential for predicting drug responses.

  • Computational Biomedecine
  • Neuro-Oncology Laboratory
  • Proteomics of cellular signaling
March 05, 2019
2019 Mar. F1000Res.7:1906.
By:
  • Azuaje F
  • Kaoma T
  • Jeanty C
  • Nazarov PV
  • Muller A
  • Kim SY
  • Dittmar G
  • Golebiewska A
  • Niclou SP.

Artificial intelligence for precision oncology: beyond patient stratification.

  • Computational Biomedecine
February 25, 2019
2019 Feb. NPJ Precis Oncol.3:6.
By:
  • Azuaje F.

Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures.

  • Neuro-Oncology Laboratory
  • Computational Biomedecine
November 01, 2018
2018 Nov. EMBO Rep.19(11). Epub 2018 Sep 11.
By:
  • Sousa C
  • Golebiewska A
  • Poovathingal SK
  • Kaoma T
  • Pires-Afonso Y
  • Martina S
  • Coowar D
  • Azuaje F
  • Skupin A
  • Balling R
  • Biber K
  • Niclou SP
  • Michelucci A.

Predicting clinical outcome of neuroblastoma patients using an integrative network-based approach.

  • Computational Biomedecine
June 07, 2018
2018 Jun. Biol Direct.13(1):12.
By:
  • Tranchevent LC
  • Nazarov PV
  • Kaoma T
  • Schmartz GP
  • Muller A
  • Kim SY
  • Rajapakse JC
  • Azuaje F.

CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT.

  • Tumor Immunotherapy and Microenvironment
  • Computational Biomedecine
February 15, 2018
2018 Feb. OncoImmunology.7(4):e1345415.
By:
  • Noman MZ
  • Van Moer K
  • Marani V
  • Gemmill RM
  • Tranchevent LC
  • Azuaje F
  • Muller A
  • Chouaib S
  • Thiery JP
  • Berchem G
  • Janji B.

Computational models for predicting drug responses in cancer research.

  • Computational Biomedecine
September 01, 2017
2017 Sep. Brief Bioinform.18(5):820-829.
By:
  • Azuaje F.

The angiogenic switch leads to a metabolic shift in human glioblastoma.

  • Neuro-Oncology Laboratory
  • Computational Biomedecine
  • Platform LUXGEN - Micro-array
March 01, 2017
2017 Mar. Neuro Oncol.19(3):383-393.
By:
  • Talasila KM
  • Rosland GV
  • Hagland HR
  • Eskilsson E
  • Flones IH
  • Fritah S
  • Azuaje F
  • Atai N
  • Harter PN
  • Mittelbronn M
  • Andersen M
  • Joseph JV
  • Hossain JA
  • Vallar L
  • Noorden CJ
  • Niclou SP
  • Thorsen F
  • Tronstad KJ
  • Tzoulis C
  • Bjerkvig R
  • Miletic H.

LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer.

  • Computational Biomedecine
September 01, 2016
2016 Sep. EMBO Mol Med.8(9):1052-64.
By:
  • Sas-Chen A
  • Aure MR
  • Leibovich L
  • Carvalho S
  • Enuka Y
  • Korner C
  • Polycarpou-Schwarz M
  • Lavi S
  • Nevo N
  • Kuznetsov Y
  • Yuan J
  • Azuaje F
  • Oslo Breast Cancer Research Consortium (OSBREAC)
  • Ulitsky I
  • Diederichs S
  • Wiemann S
  • Yakhini Z
  • Kristensen VN
  • Borresen-Dale AL
  • Yarden Y.

Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.

  • Computational Biomedecine
  • Platform LUXGEN - Micro-array
  • Neuro-Oncology Laboratory
May 31, 2016
2016 May. Sci Rep.6:26822.
By:
  • Rodius S
  • Androsova G
  • Gotz L
  • Liechti R
  • Crespo I
  • Merz S
  • Nazarov PV
  • de Klein N
  • Jeanty C
  • Gonzalez-Rosa JM
  • Muller A
  • Bernardin F
  • Niclou SP
  • Vallar L
  • Mercader N
  • Ibberson M
  • Xenarios I
  • Azuaje F.

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma.

  • Neuro-Oncology Laboratory
  • Translational Radiomics
  • Computational Biomedecine
  • Platform LUXGEN - Micro-array
  • Dimensional Immuno-Cytometry
May 31, 2016
2016 May. Oncotarget.7(22):31955-71.
By:
  • Bougnaud S
  • Golebiewska A
  • Oudin A
  • Keunen O
  • Harter PN
  • Mader L
  • Azuaje F
  • Fritah S
  • Stieber D
  • Kaoma T
  • Vallar L
  • Brons NH
  • Daubon T
  • Miletic H
  • Sundstrom T
  • Herold-Mende C
  • Mittelbronn M
  • Bjerkvig R
  • Niclou SP.

Permanent culture of macrophages at physiological oxygen attenuates the antioxidant and immunomodulatory properties of dimethyl fumarate.

  • Computational Biomedecine
May 01, 2015
2015 May. J Cell Physiol.230(5):1128-38.
By:
  • Haas B
  • Chrusciel S
  • Fayad-Kobeissi S
  • Dubois-Rande JL
  • Azuaje F
  • Boczkowski J
  • Motterlini R
  • Foresti R.

Therapeutic control and resistance of the EGFR-driven signaling network in glioblastoma.

  • Computational Biomedecine
  • Neuro-Oncology Laboratory
March 31, 2015
2015 Mar. Cell Commun Signal.13(1):23.
By:
  • Azuaje F
  • Tiemann K
  • Niclou SP.