Latest publications

The proteasome activators Blm10/PA200 enhance the proteasomal degradation of N-terminal Huntingtin.

  • Proteomics of Cellular Signaling
November 20, 2020
2020 Nov. Biomolecules.10(11).
By:
  • Aladdin A
  • Yao Y
  • Yang C
  • Kahlert G
  • Ghani M
  • Kiraly N
  • Boratko A
  • Uray K
  • Dittmar G
  • Tar K.

Nanomaterials and annelid immunity: A comparative survey to reveal the common stress and defense responses of two sentinel species to nanomaterials in the environment.

  • Proteomics of Cellular Signaling
September 23, 2020
2020 Sep. Biology.9(10).
By:
  • Bodo K
  • Baranzini N
  • Girardello R
  • Kokhanyuk B
  • Nemeth P
  • Hayashi Y
  • Grimaldi A
  • Engelmann P.

Ubiquitin chain analysis by parallel reaction monitoring.

  • Quantitative Biology Unit
  • Proteomics of Cellular Signaling
June 17, 2020
2020 Jun. J Vis Exp.(160).
By:
  • Longworth J
  • Mendes ML
  • Dittmar G.

Prognostic biomarkers in endometrial cancer: A systematic review and meta-analysis.

  • Proteomics of Cellular Signaling
June 17, 2020
2020 Jun. J Clin Med.9(6).
By:
  • Coll-de la Rubia E
  • Martinez-Garcia E
  • Dittmar G
  • Gil-Moreno A
  • Cabrera S
  • Colas E.

Influence of wood species on toxicity of log-wood stove combustion aerosols: a parallel animal and air-liquid interface cell exposure study on spruce and pine smoke.

  • Proteomics of Cellular Signaling
June 15, 2020
2020 Jun. Part Fibre Toxicol.17(1):27.
By:
  • Ihantola T
  • Di Bucchianico S
  • Happo M
  • Ihalainen M
  • Uski O
  • Bauer S
  • Kuuspalo K
  • Sippula O
  • Tissari J
  • Oeder S
  • Hartikainen A
  • Ronkko TJ
  • Martikainen MV
  • Huttunen K
  • Vartiainen P
  • Suhonen H
  • Kortelainen M
  • Lamberg H
  • Leskinen A
  • Sklorz M
  • Michalke B
  • Dilger M
  • Weiss C
  • Dittmar G
  • Beckers J
  • Irmler M
  • Buters J
  • Candeias J
  • Czech H
  • Yli-Pirila P
  • Abbaszade G
  • Jakobi G
  • Orasche J
  • Schnelle-Kreis J
  • Kanashova T
  • Karg E
  • Streibel T
  • Passig J
  • Hakkarainen H
  • Jokiniemi J
  • Zimmermann R
  • Hirvonen MR
  • Jalava PI.

In vivo crystals reveal critical features of the interaction between cystic fibrosis transmembrane conductance regulator (CFTR) and the PDZ2 domain of Na(+)/H(+) exchange cofactor NHERF1.

  • Proteomics of Cellular Signaling
April 03, 2020
2020 Apr. J Biol Chem.295(14):4464-4476. Epub 2020 Feb 2.
By:
  • Martin ER
  • Barbieri A
  • Ford RC
  • Robinson RC.

Analysis of ubiquitin signaling and chain topology cross-talk.

  • Proteomics of Cellular Signaling
March 20, 2020
2020 Mar. J Proteomics.215:103634. Epub 2020 Jan 7.
By:
  • Mendes ML
  • Fougeras MR
  • Dittmar G.

Hypoxia-Induced Adaptations of miRNomes and Proteomes in Melanoma Cells and Their Secreted Extracellular Vesicles.

  • Proteomics of Cellular Signaling
  • Quantitative Biology Unit
March 14, 2020
2020 Mar. Cancers.12(3).
By:
  • Walbrecq G
  • Lecha O
  • Gaigneaux A
  • Fougeras MR
  • Philippidou D
  • Margue C
  • Tetsi Nomigni M
  • Bernardin F
  • Dittmar G
  • Behrmann I
  • Kreis S.

Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity.

  • Proteomics of Cellular Signaling
  • Quantitative Biology Unit
  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
February 19, 2020
2020 Feb. Sci Rep.10(1):2896.
By:
  • Rodius S
  • de Klein N
  • Jeanty C
  • Sanchez-Iranzo H
  • Crespo I
  • Ibberson M
  • Xenarios I
  • Dittmar G
  • Mercader N
  • Niclou SP
  • Azuaje F.

Linear ubiquitin chains: Cellular functions and strategies for detection and quantification.

  • Proteomics of Cellular Signaling
January 10, 2020
2020 Jan. Front Chem.7:915.
By:
  • Dittmar G
  • Winklhofer KF.

Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation.

  • Proteomics of Cellular Signaling
January 01, 2020
2020 Jan. Life Sci Alliance.3(1):e201900476.
By:
  • Schuster R
  • Anton V
  • Simoes T
  • Altin S
  • den Brave F
  • Hermanns T
  • Hospenthal M
  • Komander D
  • Dittmar G
  • Dohmen RJ
  • Escobar-Henriques M.

Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1.

  • Proteomics of Cellular Signaling
October 03, 2019
2019 Oct. Elife.8.
By:
  • Zhao X
  • Nedvetsky P
  • Stanchi F
  • Vion AC
  • Popp O
  • Zuhlke K
  • Dittmar G
  • Klussmann E
  • Gerhardt H.

Connecting histopathology imaging and proteomics in kidney cancer through machine learning.

  • Multiomics Data Science
  • Proteomics of Cellular Signaling
September 25, 2019
2019 Sep. J Clin Med.8(10).
By:
  • Azuaje F
  • Kim SY
  • Perez Hernandez D
  • Dittmar G.

Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients.

  • Multiomics Data Science
  • Computational Biomedicine
  • Proteomics of Cellular Signaling
September 18, 2019
2019 Sep. BMC Med Genomics.12(1):132.
By:
  • Nazarov PV
  • Wienecke-Baldacchino AK
  • Zinovyev A
  • Czerwinska U
  • Muller A
  • Nashan D
  • Dittmar G
  • Azuaje F
  • Kreis S.

DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.

  • Proteomics of Cellular Signaling
September 06, 2019
2019 Sep. J Cell Sci.132(17).
By:
  • Nowak M
  • Suenkel B
  • Porras P
  • Migotti R
  • Schmidt F
  • Kny M
  • Zhu X
  • Wanker EE
  • Dittmar G
  • Fielitz J
  • Sommer T.

An integrated workflow for crosslinking mass spectrometry.

  • Proteomics of Cellular Signaling
September 01, 2019
2019 Sep. Mol Syst Biol.15(9):e8994.
By:
  • Mendes ML
  • Fischer L
  • Chen ZA
  • Barbon M
  • O'Reilly FJ
  • Giese SH
  • Bohlke-Schneider M
  • Belsom A
  • Dau T
  • Combe CW
  • Graham M
  • Eisele MR
  • Baumeister W
  • Speck C
  • Rappsilber J.

A protein quality control pathway regulated by linear ubiquitination.

  • Proteomics of Cellular Signaling
May 02, 2019
2019 May. EMBO J.38(9). Epub 2019 Mar 18.
By:
  • van Well EM
  • Bader V
  • Patra M
  • Sanchez-Vicente A
  • Meschede J
  • Furthmann N
  • Schnack C
  • Blusch A
  • Longworth J
  • Petrasch-Parwez E
  • Mori K
  • Arzberger T
  • Trumbach D
  • Angersbach L
  • Showkat C
  • Sehr DA
  • Berlemann LA
  • Goldmann P
  • Clement AM
  • Behl C
  • Woerner AC
  • Saft C
  • Wurst W
  • Haass C
  • Ellrichmann G
  • Gold R
  • Dittmar G
  • Hipp MS
  • Hartl FU
  • Tatzelt J
  • Winklhofer KF.

Deregulated splicing is a major mechanism of RNA-Induced toxicity in Huntington's disease.

  • Proteomics of Cellular Signaling
April 19, 2019
2019 Apr. J Mol Biol.431(9):1869-1877. Epub 2019 Jan 31.
By:
  • Schilling J
  • Broemer M
  • Atanassov I
  • Duernberger Y
  • Vorberg I
  • Dieterich C
  • Dagane A
  • Dittmar G
  • Wanker E
  • van Roon-Mom W
  • Winter J
  • Krauss S.

Assessment of ubiquitin chain topology by targeted mass spectrometry.

  • Proteomics of Cellular Signaling
April 14, 2019
2019 Apr. Methods Mol Biol.1977:25-34.
By:
  • Longworth J
  • Dittmar G.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPbeta.

  • Proteomics of Cellular Signaling
March 29, 2019
2019 Mar. iScience.13:351-370. Epub 2019 Mar 1.
By:
  • Dittmar G
  • Hernandez DP
  • Kowenz-Leutz E
  • Kirchner M
  • Kahlert G
  • Wesolowski R
  • Baum K
  • Knoblich M
  • Hofstatter M
  • Muller A
  • Wolf J
  • Reimer U
  • Leutz A.