Latest publications

Deregulated splicing is a major mechanism of RNA-Induced toxicity in Huntington's disease.

  • Proteomics of Cellular Signaling
April 19, 2019
2019 Apr. J Mol Biol.431(9):1869-1877. Epub 2019 Jan 31.
By:
  • Schilling J
  • Broemer M
  • Atanassov I
  • Duernberger Y
  • Vorberg I
  • Dieterich C
  • Dagane A
  • Dittmar G
  • Wanker E
  • van Roon-Mom W
  • Winter J
  • Krauss S.

Assessment of ubiquitin chain topology by targeted mass spectrometry.

  • Proteomics of Cellular Signaling
April 14, 2019
2019 Apr. Methods Mol Biol.1977:25-34.
By:
  • Longworth J
  • Dittmar G.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPbeta.

  • Proteomics of Cellular Signaling
March 29, 2019
2019 Mar. iScience.13:351-370. Epub 2019 Mar 1.
By:
  • Dittmar G
  • Hernandez DP
  • Kowenz-Leutz E
  • Kirchner M
  • Kahlert G
  • Wesolowski R
  • Baum K
  • Knoblich M
  • Hofstatter M
  • Muller A
  • Wolf J
  • Reimer U
  • Leutz A.

The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2, a phosphatidylserine flippase.

  • Proteomics of Cellular Signaling
March 06, 2019
2019 Mar. Biochem J.476(5):783-794.
By:
  • Theorin L
  • Faxen K
  • Sorensen DM
  • Migotti R
  • Dittmar G
  • Schiller J
  • Daleke DL
  • Palmgren M
  • Lopez-Marques RL
  • Gunther Pomorski T.

SorCS2 controls functional expression of amino acid transporter EAAT3 and protects neurons from oxidative stress and epilepsy-induced pathology.

  • Proteomics of Cellular Signaling
March 05, 2019
2019 Mar. Cell Rep.26(10):2792-2804 e6.
By:
  • Malik AR
  • Szydlowska K
  • Nizinska K
  • Asaro A
  • van Vliet EA
  • Popp O
  • Dittmar G
  • Fritsche-Guenther R
  • Kirwan JA
  • Nykjaer A
  • Lukasiuk K
  • Aronica E
  • Willnow TE.

Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress.

  • Proteomics of Cellular Signaling
February 28, 2019
2019 Feb. Sci Rep.9(1):3183.
By:
  • Jochner MCE
  • An J
  • Lattig-Tunnemann G
  • Kirchner M
  • Dagane A
  • Dittmar G
  • Dirnagl U
  • Eickholt BJ
  • Harms C.

On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility.

  • Proteomics of Cellular Signaling
November 01, 2018
2018 Nov. Mol Biol Cell.29(22):2674-2686. Epub 2018 Aug 29.
By:
  • Dolati S
  • Kage F
  • Mueller J
  • Musken M
  • Kirchner M
  • Dittmar G
  • Sixt M
  • Rottner K
  • Falcke M.

A new ALK isoform transported by extracellular vesicles confers drug resistance to melanoma cells.

  • Proteomics of Cellular Signaling
October 05, 2018
2018 Oct. Mol Cancer.17(1):145.
By:
  • Cesi G
  • Philippidou D
  • Kozar I
  • Kim YJ
  • Bernardin F
  • Van Niel G
  • Wienecke-Baldacchino A
  • Felten P
  • Letellier E
  • Dengler S
  • Nashan D
  • Haan C
  • Kreis S.

S-palmitoylation is required for the control of growth cone morphology of DRG neurons by CNP-Induced cGMP signaling.

  • Proteomics of Cellular Signaling
September 24, 2018
2018 Sep. Front Mol Neurosci.11:345.
By:
  • Dumoulin A
  • Dagane A
  • Dittmar G
  • Rathjen FG.

Queuosine-modified tRNAs confer nutritional control of protein translation.

  • Proteomics of Cellular Signaling
September 14, 2018
2018 Sep. EMBO J.37(18). Epub 2018 Aug 9.
By:
  • Tuorto F
  • Legrand C
  • Cirzi C
  • Federico G
  • Liebers R
  • Muller M
  • Ehrenhofer-Murray AE
  • Dittmar G
  • Grone HJ
  • Lyko F.

Identification of beta-arrestin-1 as a diagnostic biomarker in lung cancer.

  • Proteomics of Cellular Signaling
  • Competence Center for Methodology and Statistics
  • Computational Biomedicine
  • Clinical and Epidemiological Investigation Center
  • Integrated BioBank of Luxembourg
August 06, 2018
2018 Aug. Br J Cancer.119(5):580-590. Epub 2018 Aug 6.
By:
  • El-Khoury V
  • Beland M
  • Schritz A
  • Kim SY
  • Nazarov PV
  • Gaboury L
  • Sertamo K
  • Bernardin F
  • Batutu R
  • Antunes L
  • Bennett CW
  • Fays F
  • Berchem G
  • Kim YJ.

[Characterization of particle emissions from cutting of carbon fiber reinforced concrete (Carbon concrete composite)].

  • Proteomics of Cellular Signaling
June 01, 2018
2018 Jun. Gefahrst Reinhalt Luft.78(6):230-240.
By:
  • Hillemann L
  • Stintz M
  • Streibel T
  • Zimmermann R
  • Oder S
  • Kasurinen S
  • di Bucchianico S
  • Kanashova T
  • Dittmar G
  • Konzack D
  • Grosse S
  • Rudolph A
  • Berger M
  • Krebs T
  • Saraji-Bozorgzad MR
  • Walte A.

Development of mass spectrometry-based assays to measure the ERCC1/XPF proteins as potential biomarkers in lung cancer. (Doctoral thesis)

  • Proteomics of Cellular Signaling
May 09, 2018
2018 May. Luxembourg: Université de Luxembourg, 2018. 128 p.
By:
  • Antonelli D.

Isolation of native plasma membrane H(+)-ATPase (Pma1p) in both the active and basal activation states.

  • Proteomics of Cellular Signaling
May 01, 2018
2018 May. FEBS Open Bio.8(5):774-783.
By:
  • Pedersen JT
  • Kanashova T
  • Dittmar G
  • Palmgren M.

SORCS1 and SORCS3 control energy balance and orexigenic peptide production.

  • Proteomics of Cellular Signaling
April 01, 2018
2018 Apr. EMBO Rep.19(4). Epub 2018 Feb 12.
By:
  • Subkhangulova A
  • Malik AR
  • Hermey G
  • Popp O
  • Dittmar G
  • Rathjen T
  • Poy MN
  • Stumpf A
  • Beed PS
  • Schmitz D
  • Breiderhoff T
  • Willnow TE.

Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis.

  • Proteomics of Cellular Signaling
January 29, 2018
2018 Jan. Cell Death Discov.4(1):4.
By:
  • Matthes F
  • Hettich MM
  • Schilling J
  • Flores-Dominguez D
  • Blank N
  • Wiglenda T
  • Buntru A
  • Wolf H
  • Weber S
  • Vorberg I
  • Dagane A
  • Dittmar G
  • Wanker E
  • Ehninger D
  • Krauss S.

Analysis of cancer related protein isoforms by mass spectrometry. (Doctoral thesis)

  • Proteomics of Cellular Signaling
January 16, 2018
2018 Jan. Luxembourg: Université de Luxembourg, 2018. 154 p.
By:
  • Ancheva L.

Senescence-associated reprogramming promotes cancer stemness.

  • Proteomics of Cellular Signaling
January 04, 2018
2018 Jan. Nature.553(7886):96-100. Epub 2017 Dec 20.
By:
  • Milanovic M
  • Fan DNY
  • Belenki D
  • Dabritz JHM
  • Zhao Z
  • Yu Y
  • Dorr JR
  • Dimitrova L
  • Lenze D
  • Monteiro Barbosa IA
  • Mendoza-Parra MA
  • Kanashova T
  • Metzner M
  • Pardon K
  • Reimann M
  • Trumpp A
  • Dorken B
  • Zuber J
  • Gronemeyer H
  • Hummel M
  • Dittmar G
  • Lee S
  • Schmitt CA.

Advances in endometrial cancer protein biomarkers for use in the clinic.

  • Proteomics of Cellular Signaling
January 01, 2018
2018 Jan. Expert Rev Proteomics.15(1):81-99. Epub 2017 Nov 30.
By:
  • Martinez-Garcia E
  • Lopez-Gil C
  • Campoy I
  • Vallve J
  • Coll E
  • Cabrera S
  • Ramon YCS
  • Matias-Guiu X
  • Van Oostrum J
  • Reventos J
  • Gil-Moreno A
  • Colas E.

Targeted proteomics identifies proteomic signatures in liquid biopsies of the endometrium to diagnose endometrial cancer and assist in the prediction of the optimal surgical treatment.

  • Proteomics of Cellular Signaling
November 01, 2017
2017 Nov. Clin Cancer Res.23(21):6458-6467. Epub 2017 Aug 8.
By:
  • Martinez-Garcia E
  • Lesur A
  • Devis L
  • Cabrera S
  • Matias-Guiu X
  • Hirschfeld M
  • Asberger J
  • van Oostrum J
  • Casares de Cal MLA
  • Gomez-Tato A
  • Reventos J
  • Domon B
  • Colas E
  • Gil-Moreno A.