Latest publications

Temozolomide-induced RNA interactome uncovers novel lncRNA regulatory loops in glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Quantitative Biology Unit
  • DNA Repair and Chemoresistance
September 10, 2020
2020 Sep. Cancers.12(9).
By:
  • Fritah S
  • Muller A
  • Jiang W
  • Mitra R
  • Sarmini M
  • Dieterle M
  • Golebiewska A
  • Ye T
  • Van Dyck E
  • Herold-Mende C
  • Zhao Z
  • Azuaje F
  • Niclou SP.

A DNA repair and cell-cycle gene expression signature in primary and recurrent glioblastoma: prognostic value and clinical implications.

  • DNA Repair and Chemoresistance
  • Computational Biomedicine
  • NORLUX Neuro-Oncology Laboratory
March 15, 2019
2019 Mar. Cancer Res.79(6):1226-1238. Epub 2019 Jan 23.
By:
  • Gobin M
  • Nazarov PV
  • Warta R
  • Timmer M
  • Reifenberger G
  • Felsberg J
  • Vallar L
  • Chalmers AJ
  • Herold-Mende CC
  • Goldbrunner R
  • Niclou SP
  • Van Dyck E.

Targeted DNA repair gene expression study in glioblastoma patient biopsies: clinical impact and characterisation of the NEIL3 DNA glycosylase, a novel candidate target for therapy. (Doctoral thesis)

  • DNA Repair and Chemoresistance
March 12, 2019
2019 Mar. Luxembourg: Université de Luxembourg 2019. 156 p.
By:
  • Gobin M.

Centromeric and ectopic assembly of CENP-A chromatin in health and cancer: old marks and new tracks.

  • DNA Repair and Chemoresistance
February 20, 2019
2019 Feb. Nucleic Acids Res.47(3):1051-1069.
By:
  • Sharma AB
  • Dimitrov S
  • Hamiche A
  • Van Dyck E.

RNAi/CRISPR Screens: from a Pool to a Valid Hit.

  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
  • DNA Repair and Chemoresistance
January 01, 2019
2019 Jan. Trends Biotechnol.37(1):38-55. Epub 2018 Aug 31.
By:
  • Schuster A
  • Erasimus H
  • Fritah S
  • Nazarov PV
  • van Dyck E
  • Niclou SP
  • Golebiewska A.

Sensitizing Ewing sarcoma to chemo- and radiotherapy by inhibition of the DNA-repair enzymes DNA protein kinase (DNA-PK) and poly-ADP-ribose polymerase (PARP) 1/2.

  • DNA Repair and Chemoresistance
December 26, 2017
2017 Dec. Oncotarget.8(69):113418-113430.
By:
  • Vormoor B
  • Schlosser YT
  • Blair H
  • Sharma A
  • Wilkinson S
  • Newell DR
  • Curtin N.

Identification of DNA damage response genes as targets for personalised treatment of Glioblastoma through RNA interference screens. (Doctoral thesis)

  • DNA Repair and Chemoresistance
September 06, 2017
2017 Sep. Luxembourg: Université de Luxembourg, 2017.
By:
  • Erasimus H.

DNA repair mechanisms and their clinical impact in glioblastoma.

  • DNA Repair and Chemoresistance
  • NORLUX Neuro-Oncology Laboratory
July 01, 2016
2016 Jul. Mutat Res Rev Mutat Res.769:19-35. Epub 2016 Jun 21.
By:
  • Erasimus H
  • Gobin M
  • Niclou S
  • Van Dyck E.

Maximizing the efficacy of MAPK-targeted treatment in PTENLOF/BRAFMUT melanoma through PI3K and IGF1R inhibition.

  • DNA Repair and Chemoresistance
January 15, 2016
2016 Jan. Cancer Res.76(2):390-402. Epub 2015 Nov 17.
By:
  • Herkert B
  • Kauffmann A
  • Molle S
  • Schnell C
  • Ferrat T
  • Voshol H
  • Juengert J
  • Erasimus H
  • Marszalek G
  • Kazic-Legueux M
  • Billy E
  • Ruddy D
  • Stump M
  • Guthy D
  • Ristov M
  • Calkins K
  • Maira SM
  • Sellers WR
  • Hofmann F
  • Hall MN
  • Brachmann SM.

The pH sensibility of actin-bundling LIM proteins is governed by the acidic properties of their C-terminal domain.

  • Cytoskeleton and Cancer Progression
  • NORLUX Neuro-Oncology Laboratory
  • DNA Repair and Chemoresistance
August 19, 2015
2015 Aug. FEBS Lett.589(18):2312-9. Epub 2015 Jul 29.
By:
  • Moes D
  • Hoffmann C
  • Dieterle M
  • Moreau F
  • Neumann K
  • Papuga J
  • Furtado AT
  • Steinmetz A
  • Thomas C.