Latest publications

Endothelial Epas1 deficiency Is sufficient to promote parietal epithelial cell activation and FSGS in experimental hypertension.

  • Platform National Cytometry
December 01, 2017
2017 Dec. J Am Soc Nephrol.28(12):3563-3578. Epub 2017 Sep 19.
By:
  • Luque Y
  • Lenoir O
  • Bonnin P
  • Hardy L
  • Chipont A
  • Placier S
  • Vandermeersch S
  • Xu-Dubois YC
  • Robin B
  • Lazareth H
  • Souyri M
  • Guyonnet L
  • Baudrie V
  • Camerer E
  • Rondeau E
  • Mesnard L
  • Tharaux PL.

Bone marrow-derived mesenchymal stem cell-loaded fibrin patches act as a reservoir of paracrine factors in chronic myocardial infarction.

  • Platform National Cytometry
December 01, 2017
2017 Dec. J Tissue Eng Regen Med.11(12):3417-3427. Epub 2017 Feb 3.
By:
  • Blondiaux E
  • Pidial L
  • Autret G
  • Rahmi G
  • Balvay D
  • Audureau E
  • Wilhelm C
  • Guerin CL
  • Bruneval P
  • Silvestre JS
  • Menasche P
  • Clement O.

Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
  • Platform National Cytometry
October 31, 2017
2017 Oct. Proc Natl Acad Sci U S A.114(44):E9271-E9279. Epub 2017 Oct 16.
By:
  • Mgrditchian T
  • Arakelian T
  • Paggetti J
  • Noman MZ
  • Viry E
  • Moussay E
  • Van Moer K
  • Kreis S
  • Guerin C
  • Buart S
  • Robert C
  • Borg C
  • Vielh P
  • Chouaib S
  • Berchem G
  • Janji B.

Co-injection of mesenchymal stem cells with endothelial progenitor cells accelerates muscle recovery in hind limb ischemia through an endoglin-dependent mechanism.

  • Platform National Cytometry
October 05, 2017
2017 Oct. Thromb Haemost.117(10):1908-1918. Epub 2017 Aug 3.
By:
  • Rossi E
  • Smadja D
  • Goyard C
  • Cras A
  • Dizier B
  • Bacha N
  • Lokajczyk A
  • Guerin CL
  • Gendron N
  • Planquette B
  • Mignon V
  • Bernabeu C
  • Sanchez O
  • Smadja DM.

Human very small embryonic-like cells support vascular maturation and therapeutic revascularization induced by endothelial progenitor cells.

  • Platform National Cytometry
August 01, 2017
2017 Aug. Stem Cell Rev.13(4):552-560.
By:
  • Guerin CL
  • Rossi E
  • Saubamea B
  • Cras A
  • Mignon V
  • Silvestre JS
  • Smadja DM.

Very small embryonic-like stem cells are mobilized in human peripheral blood during hypoxemic COPD exacerbations and pulmonary hypertension.

  • Platform National Cytometry
August 01, 2017
2017 Aug. Stem Cell Rev.13(4):561-566.
By:
  • Guerin CL
  • Blandinieres A
  • Planquette B
  • Silvestre JS
  • Israel-Biet D
  • Sanchez O
  • Smadja DM.

The endothelin B receptor plays a crucial role in the adhesion of neutrophils to the endothelium in sickle cell disease.

  • Platform National Cytometry
July 01, 2017
2017 Jul. Haematologica.102(7):1161-1172. Epub 2017 Apr 6.
By:
  • Koehl B
  • Nivoit P
  • El Nemer W
  • Lenoir O
  • Hermand P
  • Pereira C
  • Brousse V
  • Guyonnet L
  • Ghinatti G
  • Benkerrou M
  • Colin Y
  • Le Van Kim C
  • Tharaux PL.

Tumour-associated glial host cells display a stem-like phenotype with a distinct gene expression profile and promote growth of GBM xenografts.

  • Platform National Cytometry
February 17, 2017
2017 Feb. BMC Cancer.17(1):108.
By:
  • Leiss L
  • Mutlu E
  • Oyan A
  • Yan T
  • Tsinkalovsky O
  • Sleire L
  • Petersen K
  • Rahman MA
  • Johannessen M
  • Mitra SS
  • Jacobsen HK
  • Talasila KM
  • Miletic H
  • Jonassen I
  • Li X
  • Brons NH
  • Kalland KH
  • Wang J
  • Enger PO.

Maintenance therapy with histamine plus IL-2 induces a striking expansion of two CD56bright NK cell subpopulations in patients with acute myeloid leukemia and supports their activation.

  • Platform National Cytometry
July 19, 2016
2016 Jul. Oncotarget.7(29):46466-46481.
By:
  • Cuapio A
  • Post M
  • Cerny-Reiterer S
  • Gleixner KV
  • Stefanzl G
  • Basilio J
  • Herndlhofer S
  • Sperr WR
  • Brons NH
  • Casanova E
  • Zimmer J
  • Valent P
  • Hofer E.

Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction.

  • Platform National Cytometry
June 27, 2016
2016 Jun. J Exp Med.213(7):1353-74.
By:
  • Ngkelo A
  • Richart A
  • Kirk JA
  • Bonnin P
  • Vilar J
  • Lemitre M
  • Marck P
  • Branchereau M
  • Le Gall S
  • Renault N
  • Guerin C
  • Ranek MJ
  • Kervadec A
  • Danelli L
  • Gautier G
  • Blank U
  • Launay P
  • Camerer E
  • Bruneval P
  • Menasche P
  • Heymes C
  • Luche E
  • Casteilla L
  • Cousin B
  • Rodewald HR
  • Kass DA
  • Silvestre JS.

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Computational Biomedicine
  • Platform LUXGEN - Micro-Array
  • Platform National Cytometry
May 31, 2016
2016 May. Oncotarget.7(22):31955-71.
By:
  • Bougnaud S
  • Golebiewska A
  • Oudin A
  • Keunen O
  • Harter PN
  • Mader L
  • Azuaje F
  • Fritah S
  • Stieber D
  • Kaoma T
  • Vallar L
  • Brons NH
  • Daubon T
  • Miletic H
  • Sundstrom T
  • Herold-Mende C
  • Mittelbronn M
  • Bjerkvig R
  • Niclou SP.

Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • Platform National Cytometry
  • NORLUX Neuro-Oncology Laboratory
August 01, 2014
2014 Aug. Leukemia.28(8):1636-46. Epub 2014 Jan 14.
By:
  • El-Khoury V
  • Pierson S
  • Szwarcbart E
  • Brons NH
  • Roland O
  • Cherrier-De Wilde S
  • Plawny L
  • Van Dyck E
  • Berchem G.

NK cell killer Ig-like receptor repertoire acquisition and maturation are strongly modulated by HLA class I molecules.

  • Platform National Cytometry
March 15, 2014
2014 Mar. J Immunol.192(6):2602-10. Epub 2014 Feb 19.
By:
  • Sleiman M
  • Brons NH
  • Kaoma T
  • Dogu F
  • Villa-Forte A
  • Lenoble P
  • Hentges F
  • Kotsch K
  • Gadola SD
  • Vilches C
  • Zimmer J.

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

  • NORLUX Neuro-Oncology Laboratory
  • Platform National Cytometry
  • Platform LUXGEN - Micro-Array
February 01, 2014
2014 Feb. Acta Neuropathol.127(2):203-1. Epub 2013 Oct 24.
By:
  • Stieber D
  • Golebiewska A
  • Evers L
  • Lenkiewicz E
  • Brons NH
  • Nicot N
  • Oudin A
  • Bougnaud S
  • Hertel F
  • Bjerkvig R
  • Vallar L
  • Barrett MT
  • Niclou SP.

Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells.

  • NORLUX Neuro-Oncology Laboratory
  • Platform National Cytometry
  • Platform LUXGEN - Micro-Array
May 01, 2013
2013 May. Brain.136(Pt 5):1462-75. Epub 2013 Mar 4.
By:
  • Golebiewska A
  • Bougnaud S
  • Stieber D
  • Brons NH
  • Vallar L
  • Hertel F
  • Klink B
  • Schrock E
  • Bjerkvig R
  • Niclou SP.

Mouse lung and spleen natural killer cells have phenotypic and functional differences, in part influenced by macrophages.

  • Platform National Cytometry
December 12, 2012
2012 Dec. PLoS One.7(12):e51230. Epub 2012 Dec 5.
By:
  • Michel T
  • Poli A
  • Domingues O
  • Mauffray M
  • Theresine M
  • Brons NH
  • Hentges F
  • Zimmer J.

Interindividual variability and co-regulation of DNA methylation differ among blood cell populations.

  • Clinical and Applied Virology
  • Platform National Cytometry
December 01, 2012
2012 Dec. Epigenetics.7(12):1421-34. Epub 2012 Nov 14.
By:
  • Jacoby M
  • Gohrbandt S
  • Clausse V
  • Brons NH
  • Muller CP.

Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Platform National Cytometry
October 01, 2011
2011 Oct. Acta Neuropathol.122(4):495-510. Epub 2011 Aug 24.
By:
  • Svendsen A
  • Verhoeff JJ
  • Immervoll H
  • Brogger JC
  • Kmiecik J
  • Poli A
  • Netland IA
  • Prestegarden L
  • Planaguma J
  • Torsvik A
  • Kjersem AB
  • Sakariassen PO
  • Heggdal JI
  • Van Furth WR
  • Bjerkvig R
  • Lund-Johansen M
  • Enger PO
  • Felsberg J
  • Brons NH
  • Tronstad KJ
  • Waha A
  • Chekenya M.

Detection of differentially modified pathogen proteins by western blot after 2D Gel electrophoresis and identification by MALDI-TOF/TOF. In BSL3 and BSL4 Agents: Proteomics, Glycomics, and Antigenicity. (Book Chapter)

  • NORLUX Neuro-Oncology Laboratory
  • Platform National Cytometry
  • Clinical and Applied Virology
September 30, 2011
2011 Sep. Stulik J, Toman R, Butaye P and Ulrich RG, eds. Weinheim: Wiley-VCH Verlag, 2011. p.131-138. ISBN 9783527327805.
By:
  • Fack F
  • Kessler JR
  • Pirrotte P
  • Kremer JR
  • Revets D
  • Ammerlaan W
  • Muller CP.

Anti-cancer effects of 20(S)-protopanoxadiol on human acute lymphoblastic leukemia cell lines Reh and RS4;11.

  • Platform National Cytometry
September 01, 2011
2011 Sep. Med Oncol.28(3):813-21. Epub 2010 Mar 31.
By:
  • Sun L
  • Wang Q
  • Liu X
  • Brons NH
  • Wang N
  • Steinmetz A
  • Lv Y
  • Liao Y
  • Zheng H.