Latest publications

Method for the analysis of the tumor microenvironment by mass cytometry: Application to chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • Platform National Cytometry
October 20, 2020
2020 Oct. Front Immunol.11:578176.
By:
  • Gonder S
  • Fernandez Botana I
  • Wierz M
  • Pagano G
  • Gargiulo E
  • Cosma A
  • Moussay E
  • Paggetti J
  • Largeot A.
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Diagnostic and therapeutic potential of extracellular vesicles in B-cell malignancies.

  • Tumor Stroma Interactions
September 29, 2020
2020 Sep. Front Oncol.10(2057):580874.
By:
  • Gargiulo E
  • Morande PE
  • Largeot A
  • Moussay E
  • Paggetti J.
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Characterisation of the tumour microenvironment in chronic lymphocytic leukemia by mass cytometry: implications for immunotherapy. (Doctoral thesis)

  • Tumor Stroma Interactions
September 14, 2020
2020 Sep. Paris: University Paris-Saclay, 2020. 271 p.
By:
  • Wierz M.
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Actin remodeling and vesicular trafficking at the tumor cell side of the immunological synapse direct evasion from cytotoxic lymphocytes.

  • Cytoskeleton and Cancer Progression
  • Tumor Stroma Interactions
September 09, 2020
2020 Sep. Int Rev Cell Mol Biol.356:99-130. Epub 2020 Sep.
By:
  • Biolato AM
  • Filali L
  • Wurzer H
  • Hoffmann C
  • Gargiulo E
  • Valitutti S
  • Thomas C.
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Hematological malignancy-derived small extracellular vesicles and tumor microenvironment: The art of turning foes into friends.

  • Tumor Stroma Interactions
May 27, 2019
2019 May. Cells.8(5):pii: E511.
By:
  • Gargiulo E
  • Paggetti J
  • Moussay E.
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The B-side of cancer immunity: The underrated tune.

  • Tumor Stroma Interactions
May 13, 2019
2019 May. Cells.8(5):pii: E449.
By:
  • Largeot A
  • Pagano G
  • Gonder S
  • Moussay E
  • Paggetti J.
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HSP110 translocates to the nucleus upon genotoxic chemotherapy and promotes DNA repair in colorectal cancer cells.

  • Tumor Stroma Interactions
April 01, 2019
2019 Apr. Oncogene.38(15):2767-2777. Epub 2018 Dec 12.
By:
  • Causse SZ
  • Marcion G
  • Chanteloup G
  • Uyanik B
  • Boudesco C
  • Grigorash BB
  • Douhard R
  • Dias AMM
  • Dumetier B
  • Dondaine L
  • Gozzi GJ
  • Moussay E
  • Paggetti J
  • Mirjolet C
  • de Thonel A
  • Dubrez L
  • Demidov ON
  • Gobbo J
  • Garrido C.
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Purification of leukemia-derived exosomes to study microenvironment modulation.

  • Tumor Stroma Interactions
  • Platform National Cytometry
January 01, 2019
2019 Jan. Methods Mol Biol.1884:231-245.
By:
  • Wierz M
  • Pierson S
  • Gargiulo E
  • Guerin C
  • Moussay E
  • Paggetti J.
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Transgenic expression of the RNA binding protein IMP2 stabilizes miRNA targets in murine microsteatosis.

  • Tumor Stroma Interactions
October 01, 2018
2018 Oct. Biochim Biophys Acta Mol Basis Dis.1864(10):3099-3108. Epub 2018 May 30.
By:
  • Dehghani Amirabad A
  • Ramasamy P
  • Wierz M
  • Nordstrom K
  • Kessler SM
  • Schulz MH
  • Simon M.
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High-dimensional mass cytometry analysis revealed microenvironment complexity in chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • Tumor Immunotherapy and Microenvironment
May 24, 2018
2018 May. OncoImmunology.7(8):e1465167.
By:
  • Wierz M
  • Janji B
  • Berchem G
  • Moussay E
  • Paggetti J.
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Driving Natural Killer cells toward the melanoma tumor battlefield: Autophagy as a valuable therapeutic target.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
April 25, 2018
2018 Apr. OncoImmunology.7(8):e1452583.
By:
  • Noman MZ
  • Paggetti J
  • Moussay E
  • Berchem G
  • Janji B.
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Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • Platform National Cytometry
  • Tumor Immunotherapy and Microenvironment
  • NORLUX Neuro-Oncology Laboratory
  • Allergy and Clinical Immunology
April 05, 2018
2018 Apr. Blood.131(14):1617-1621. Epub 2018 Feb 13.
By:
  • Wierz M
  • Pierson S
  • Guyonnet L
  • Viry E
  • Lequeux A
  • Oudin A
  • Niclou SP
  • Ollert M
  • Berchem G
  • Janji B
  • Guerin C
  • Paggetti J
  • Moussay E.
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The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells ex vivo but fails to prevent leukemia development in a murine model.

  • Tumor Stroma Interactions
April 01, 2018
2018 Apr. Haematologica.103(4):e154-e157. Epub 2018 Jan 5.
By:
  • Wierz M
  • Pierson S
  • Chouha N
  • Desaubry L
  • Francois JH
  • Berchem G
  • Paggetti J
  • Moussay E.
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Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
  • Platform National Cytometry
October 31, 2017
2017 Oct. Proc Natl Acad Sci U S A.114(44):E9271-E9279. Epub 2017 Oct 16.
By:
  • Mgrditchian T
  • Arakelian T
  • Paggetti J
  • Noman MZ
  • Viry E
  • Moussay E
  • Van Moer K
  • Kreis S
  • Guerin C
  • Buart S
  • Robert C
  • Borg C
  • Vielh P
  • Chouaib S
  • Berchem G
  • Janji B.
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Tumor-derived exosomes modulate PD-L1 expression in monocytes.

  • Tumor Stroma Interactions
July 28, 2017
2017 Jul. Sci Immunol.2(13):pii: eaah5509.
By:
  • Haderk F
  • Schulz R
  • Iskar M
  • Cid LL
  • Worst T
  • Willmund KV
  • Schulz A
  • Warnken U
  • Seiler J
  • Benner A
  • Nessling M
  • Zenz T
  • Gobel M
  • Durig J
  • Diederichs S
  • Paggetti J
  • Moussay E
  • Stilgenbauer S
  • Zapatka M
  • Lichter P
  • Seiffert M.
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Expanding the interactome of TES by exploiting TES modules with different subcellular localizations.

  • Tumor Stroma Interactions
May 05, 2017
2017 May. J Proteome Res.16(5):2054-2071. Epub 2017 Apr 20.
By:
  • Sala S
  • Van Troys M
  • Medves S
  • Catillon M
  • Timmerman E
  • Staes A
  • Schaffner-Reckinger E
  • Gevaert K
  • Ampe C.
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Hijacker of the antitumor immune response: autophagy is showing its worst facet.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
November 18, 2016
2016 Nov. Front Oncol.6(246):246.
By:
  • Viry E
  • Noman MZ
  • Arakelian T
  • Lequeux A
  • Chouaib S
  • Berchem G
  • Moussay E
  • Paggetti J
  • Janji B.
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A high rate of telomeric sister chromatid exchange occurs in chronic lymphocytic leukaemia B-cells.

  • Tumor Stroma Interactions
  • Integrated BioBank of Luxembourg
  • Laboratory of Oncolytic-Virus-Immuno-Therapeutics
July 01, 2016
2016 Jul. Br J Haematol.174(1):57-70. Epub 2016 Mar 11.
By:
  • Medves S
  • Auchter M
  • Chambeau L
  • Gazzo S
  • Poncet D
  • Grangier B
  • Verney A
  • Moussay E
  • Ammerlaan W
  • Brisou G
  • Morjani H
  • Geli V
  • Palissot V
  • Berchem G
  • Salles G
  • Wenner T.
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The multifaceted role of autophagy in tumor evasion from immune surveillance.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
April 05, 2016
2016 Apr. Oncotarget.7(14):17591-607.
By:
  • Janji B
  • Viry E
  • Moussay E
  • Paggetti J
  • Arakelian T
  • Mgrditchian T
  • Messai Y
  • Noman MZ
  • Van Moer K
  • Hasmim M
  • Mami-Chouaib F
  • Berchem G
  • Chouaib S.
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Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-beta and miR23a transfer.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
April 01, 2016
2016 Apr. OncoImmunology.5(4):e1062968. Epub 2015 Jun 24.
By:
  • Berchem G
  • Noman MZ
  • Bosseler M
  • Paggetti J
  • Baconnais S
  • Le Cam E
  • Nanbakhsh A
  • Moussay E
  • Mami-Chouaib F
  • Janji B
  • Chouaib S.
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