Activities

The identification, isolation and characterization of allergens is crucial for diagnosis and therapy of allergic disorders. The team focuses on the analysis of respiratory and food allergens from animal origin. A large panel of characterized fish and furry pet allergens became available during the past decade.

The use of single allergens in IgE-diagnosis allows to discriminate between a primary sensitization and cross-reactivity, a first step into personalized diagnosis and treatment. We are closely linked to the clinic through our partner, the National Service of Immuno-Allergology at CHL. The analysis of common allergen features helps to understand the allergic immune response and as a perspective, to develop strategies for patient immunotherapy.

Research projects

  • Analysis of respiratory allergens from small furry animals
  • Analysis of food allergens from fish and meat
  • Developing strategies for improved patient diagnosis, care and treatment

Featured Publications

Spatial distribution of alpha-gal in Ixodes ricinus - A histological study.

  • Molecular and Translational Allergology
September 01, 2020
2020 Sep. Ticks Tick Borne Dis.11(5):101506.
By:
  • Fischer J
  • Riel S
  • Fehrenbacher B
  • Frank A
  • Schaller M
  • Biedermann T
  • Hilger C
  • Mackenstedt U.

Negative oral provocation test with porcine pancreatic enzyme plus cofactors despite confirmed alpha-Gal syndrome.

  • Molecular and Translational Allergology
June 03, 2020
2020 Jun. J Investig Allergol Clin Immunol.30(6). Online ahead of print.
By:
  • Eberlein B
  • Mehlich J
  • Reidenbach K
  • Pilz C
  • Hilger C
  • Darsow U
  • Brockow K
  • Biedermann T.
See all publications

Contacts

Christiane Hilger

Ph.D.

29, rue Henri Koch
L-4354Esch-sur-Alzette
Luxembourg
Tel. : +352 26970-258

Annette KUEHN

PhD

29, rue Henri Koch
L-4354 Esch-Sur-Alzette
LUXEMBOURG
Tel. : +352 26 970 335