The identification, isolation and characterization of allergens is crucial for diagnosis and therapy of allergic disorders. The team focuses on the analysis of respiratory and food allergens from animal origin. A large panel of characterized fish and furry pet allergens became available during the past decade.

The use of single allergens in IgE-diagnosis allows to discriminate between a primary sensitization and cross-reactivity, a first step into personalized diagnosis and treatment. We are closely linked to the clinic through our partner, the National Service of Immuno-Allergology at CHL. The analysis of common allergen features helps to understand the allergic immune response and as a perspective, to develop strategies for patient immunotherapy.

Research projects

  • Analysis of respiratory allergens from small furry animals
  • Analysis of food allergens from fish and meat
  • Developing strategies for improved patient diagnosis, care and treatment

Featured Publications

Spatial distribution of alpha-gal in Ixodes ricinus - A histological study.

  • Molecular and Translational Allergology
September 01, 2020
2020 Sep. Ticks Tick Borne Dis.11(5):101506.
  • Fischer J
  • Riel S
  • Fehrenbacher B
  • Frank A
  • Schaller M
  • Biedermann T
  • Hilger C
  • Mackenstedt U.

Negative oral provocation test with porcine pancreatic enzyme plus cofactors despite confirmed alpha-Gal syndrome.

  • Molecular and Translational Allergology
June 03, 2020
2020 Jun. J Investig Allergol Clin Immunol.30(6). Online ahead of print.
  • Eberlein B
  • Mehlich J
  • Reidenbach K
  • Pilz C
  • Hilger C
  • Darsow U
  • Brockow K
  • Biedermann T.
See all publications


Christiane Hilger


29, rue Henri Koch
Tel. : +352 26970-258

Annette KUEHN


29, rue Henri Koch
L-4354 Esch-Sur-Alzette
Tel. : +352 26 970 335