Quantity and quality of sleep as a potential target to prevent diabetes in the general population
A collaborative effort from the Luxembourg Institute of Health (LIH), the University of Western Ontario (Canada), Aarhus University (Denmark), the Steno Diabetes Center Aarhus (Denmark), the Centre Hospitalier de Luxembourg (CHL) and the Directorate of Health (Luxembourg), led by Dr Gloria A. Aguayo from the LIH Department of Population Health (DoPH), was the first to show a link between poor sleep quality and duration, and impaired glycaemic control. The results, published in Diabetes & Metabolism in May 2021, highlight the relevance of measuring sleep patterns as key factors in the prevention of diabetes.
[Press release] New Study Further Advances the Treatment of Chronic Pain
Building on their previous findings, scientists from the Immuno-Pharmacology and Interactomics group at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH), in collaboration with the Center for Drug Discovery at RTI International (RTI), a nonprofit research institute, have demonstrated that conolidine, a natural painkiller derived from the pinwheel flower and traditionally used in Chinese medicine, interacts with the newly identified opioid receptor ACKR3/CXCR7 that regulates opioid peptides naturally produced in the brain. The researchers also developed a synthetic analogue of conolidine, RTI-5152-12, which displays an even greater activity on the receptor. These findings, which were published on June 3rd in the prestigious international journal ‘Signal Transduction and Targeted Therapy’ (Nature publishing group), further advance the understanding of pain regulation and open alternative therapeutic avenues for the treatment of chronic pain.
LIH cancer research supported by Schëfflenger Kriibshëllef donation
On May 20th 2021, the Luxembourgish non-profit association “Schëfflenger Kriibshëllef” made a donation to the LIH Department of Oncology (DONC) to support the acquisition of new laboratory equipment for cancer research.
A year of Predi-COVID
On May 5th 2020, the first participants were being enrolled in the newly launched Predi-COVID cohort. Fast-forward to May 2021, these initial volunteers have been invited to take part in the final follow-up foreseen under the study, which will specifically seek to shed light on the features of “Long COVID” through a new dedicated questionnaire.
[Press release] Luxembourg hosts international flagship cancer epidemiology conference
From May 12th until May 14th, about 150 international scientists, clinicians, healthcare professionals and policymakers from 17 nations will gather for the 45th edition of the Group of Cancer Epidemiology and Registration in Latin Language Countries (GRELL) conference which, due to the current pandemic, will take place in a fully virtual format. Organised in Luxembourg for the first time by the National Cancer Registry of Luxembourg (Registre National du Cancer - RNC) at the Luxembourg Institute of Health (LIH), the meeting will feature several prominent speakers, providing an opportunity to discuss the latest developments in the field of cancer epidemiology with a particular focus on COVID-19 and cancer, as well as childhood and adolescent cancers. This 2021 edition of the GRELL conference is dedicated to the memory of the late Dr Michel Untereiner, oncologist and Scientific Director of the RNC between January 2013 and March 2021.
Visceral adiposity and cardiometabolic health in Luxembourg
Looking at a sample of individuals representative of the Luxembourgish population, researchers from the LIH Department of Population Health (DoPH) showed that increased visceral adipose tissue (VAT), located inside the abdominal cavity between the organs, is strongly associated with an increased risk of developing cardiometabolic disorders. To study this relationship, the scientists used recently developed and validated anthropometric predictive models of VAT, which distinguished VAT from other forms of adipose tissue. Their findings were published in the April issue of the Nature Publishing Group journal “Scientific Reports”.
Luxembourg and Canada researchers join forces
Following a first call for proposals in December 2020, a bilateral project involving the Human Biomonitoring Research Unit (HBRU) of the LIH Department of Population Health (DoPH) and the University of Québec in Montréal (UQAM) was selected for funding on March 29th under the Québec-Luxembourg programme AUDACE, a joint initiative of the Luxembourg National Research Fund (FNR) and of the Quebec Research Fund (FRQ). The scheme aims to support innovative and high-impact interdisciplinary and intersectoral collaborations between Quebec and Luxembourg scientists.
Internship in Obesity Paradox & Cardiovascular Health: Oriscav data (Master Students) - HSYD0621
To be part of a joint research project of the “Nutrition & Health Research Group” (Scientist: Hanen Samouda, PhD) and the “Cardiovascular Research Unit” (Group Leader: Yvan Devaux, PhD) within the Department of Population Health at the LIH, we are currently looking for a Master Student in Obesity Paradox & Cardiovascular Health: Oriscav data .